Skin Cancer Statistics More than 1,000,000 people will be diganosed with skin cancer this year. More people have skin cancer than prostate, breast, lung, colon, and bladder cancer combined. Approximately 9,800 Americans will die from skin cancer this year. It is estimated that about 60% of American over 40 have at least one precancerous skin lesion. At least 40% of Americans who live to the age of 65 will have at least one skin cancer