Skin Cancer Treatment Actinic Keratosis May be frozen with liquid nitrogen May be treated with drugs applied to the skin Squamous Cell and Basal Cell Cancer May be frozen with liquid nitrogen May be removed by curettage (scraping) and electrodesiccation (cautery) May be removed by simple excision (office surgery) May be removed by Mohs micrographic surgery - a surgery performed by a specially trained dermatologist that removes small parts of the skin, checks them for cancer under a microscope, then continues to remove small parts of the skin until the cancer is completely gone. Melanoma Must be removed by sugical excision with wide margin May require chemotherapy and/or radiation therapy.